专利摘要:
The invention relates to a housing for a laboratory device with bottom (2), ceiling (4), rear wall (5), side walls (6) and front wall (7), which together form a working space (8) enclosed by them. The front wall (7) is movable between a closed position and an open position. In the working space (8) a working area (13) aligned in a plane is provided, in which liquids can be handled. A filter device (14) for ambient air is fluidly connected via at least one air outlet (15) to the working space (8) of the housing (1). It has at least one air inlet (16) connected to the environment and downstream of the air inlet (16) and upstream of the air outlet (15) a fan (17) and an air filter (18). On the housing there is also an outflow opening (20). The at least one air outlet (15) on the one hand and the at least one outflow opening (20) on the other hand are arranged on the housing (1) so that the filter air flow (19) is substantially parallel to and along the working area (13) during operation of the filter device (14). flows.
公开号:CH712504A2
申请号:CH00611/17
申请日:2017-05-08
公开日:2017-11-30
发明作者:Petek Max;Jungbluth Martin;Weiner Christian;Berberich Christian;Gehrig Steffen;Howe Thomas;H Mahler Peter;Peszleg Benjamin
申请人:Brand Gmbh + Co Kg;
IPC主号:
专利说明:

Description: [0001] The invention relates to a housing for a laboratory device having the features of the preamble of claim 1.
In the prior art, from which the invention proceeds (DE 60 2004 010 578 T2), located in the working space of the housing, a laboratory device in the form of a device for receiving animal cell colonies. A camera movable by means of a positioning device identifies animal cell colonies in a medium which is located in a sample container. By means of a recording head movable parallel to the camera, the medium is drawn in from one of the sample containers and transferred in each case to another sample container. The sample containers are located in a working area in the working area, which is aligned in a horizontal plane. The working space with the laboratory device located therein is surrounded by a largely gas-tight housing. On the ceiling of the housing a filter device is mounted. The working space in the housing can be kept substantially free of contaminating particles by means of the filter device. This is done by supplying a filtered filter air flow through the at least one HEPA filter as an air filter having filter device in the working space, so that the working space is always under a slight overpressure against the air pressure in the environment. This prevents the inevitable existing column in the housing air from the environment penetrates into the workspace.
In the previously described, known housing for a laboratory device with a filter device through which an air outlet from a constant filter air flow is conveyed into the working space inside, the air escapes from the working space in the housing inevitably existing column in the housing, which in particular on the movable front wall, via which the working space is accessible from outside. The filter air flow in the working space flows through the workspace defined in the working space in which the laboratory equipment is located, in different, not previously defined directions, in particular from above from the air outlet to the filter device down and then in the direction of the front wall of the housing. The filter air flow crosses with particles adhering contaminated parts, for example, a moving device for laboratory equipment.
Similar circumstances can also be found in known from practice housings for laboratory equipment, such as pipetting robot. Their housing must be closed for safety reasons during the operation of moving laboratory equipment.
The invention is based on the object, the known housing for a laboratory device, which is equipped with a filter device that promotes a filter air flow into the working space, so design and further that the filter air flow passes through the working area in the working space in a well-defined way ,
The above-mentioned object is achieved in a housing for a laboratory device having the features of the preamble of claim 1 by the features of the characterizing part of claim 1.
According to the invention is not, as in the prior art, based on the fact that the working space is kept permanently under a slight overpressure, this overpressure degrades only through leaks on unavoidably existing column on the housing, but it is envisaged that the housing in a coordinated with the position of the at least one air outlet area at least one discharge opening is deliberately structurally provided. In the housing according to the invention, with the at least one air outlet and the at least one outflow opening, the decisive parameters are to keep the filter air flow laminar in the working area and to largely guide it, regardless of where and how otherwise leaks are unavoidable and untargeted ,
For this purpose, the invention provides that the at least one air outlet on the one hand and the at least one outflow opening on the other hand are arranged on the housing so that when operating the filter device, the filter air flow substantially parallel to and along the work area, preferably substantially horizontally by the and / or along the work area, flows. The sample containers and other auxiliary containers or devices used in the work area are frequently exchanged and are contaminated with particles and germs. A laminar, straight-line stream of filter air over the working area prevents contamination of the media held in the containers or their transfer by pipette tips.
The laboratory equipment and the movement device for the laboratory equipment in the work area can inevitably occur deflections and turbulence in the filter air flow. However, the flow of the filter air flow substantially parallel to and along the work area reduces this undefined flow to a minimum.
It is particularly preferred if the arrangement of the at least one air outlet and the at least one outflow opening is made so that the filter air flow substantially horizontally in the working space (taking into account the possibly existing deflections, as described above) by and / or flows along the work area.
In the prior art, the filter air flow is directed substantially vertically from the ceiling into the working space. A thus aligned vertical filter air flow blows on a portal of the moving device dust in the work area. In contrast, in the case of the construction according to the invention, a substantially horizontal, ie parallel to the working area, and also, preferably, a substantially rectilinear directed filter air flow results. Thus, contamination of media is largely prevented by the orientation of the filter air flow in the working space. Measurements have shown that clean room class 5 in accordance with IS0 14644-1 or aseptic air quality levels in accordance with the manufacturing process guidelines for the pharmaceutical industry (GMP 2007) can be achieved in the work area.
Preferred embodiments and further developments of the teaching of the invention are the subject of the dependent claims. The explanation of the advantages of the invention and the explanation of preferred embodiments and further developments takes place in connection with the explanation of the preferred embodiments with reference to the drawing.
The invention will be explained in more detail with reference to a drawing illustrating a particularly preferred embodiment. In the drawing shows
1 is a perspective view of a housing according to the invention with befindliches in closing position front wall,
2 shows the housing of FIG. 1 with the front wall in the open position, FIG.
3 shows the housing of FIG. 1 in section,
4 shows the housing of FIG. 2 in section,
5 shows the housing of FIG. 1 in a plan view,
6 is a designed as a separate assembly filter device for a housing according to FIG. 1 in a perspective view,
7 shows a flow chart for the filter air flow in a housing according to the invention.
The invention relates to a housing 1 for a laboratory device. The housing 1 has a base 2 here with support legs 3, a ceiling 4 closing the housing 1 at the top, a rear wall 5, side walls 6 and a front wall 7. Together, the parts 2, 4, 5 and 6 enclose a working space 8.
In the illustrated and insofar preferred embodiment, which can be illustrated in connection with FIGS. 1 to 4, located in the working space 8 of the housing 1 as a laboratory device 9, a pipetting robot, in the illustrated and preferred embodiment, a movement device 10 for laboratory equipment 11th in the form of pipettes. The pipettes interact with the media in different sample receiving plates 12 with the aid of the pipetting robot.
From a compound of Fig. 1, showing the closed housing 1, with Fig. 2, showing the open housing 1, it can be seen that the front wall 7 between a shown in Fig. 1 lowered closing position and a in Fig. 2 shown raised opening position is movable. As shown in FIG. 2, the working space 8 in the opening position of the front wall 7 on the front side is substantially open.
In the illustrated embodiment, the side walls 6 of the housing 1 are fixed. It can also be used side walls 6 as in the above-described prior art, which can be opened. For details of the construction of the concretely illustrated embodiment of a housing 1, reference is made in its entirety to the prior art from DE 20 2014 001 872 U1.
For the present invention in the focus of interest, it is important that in the working space 8 a aligned in a horizontal plane working area 13 is provided, can be handled in the liquids. The work area 13 has been drawn in dash-dotted lines in each case in FIGS. 3 and 4. It represents the area in which the handling of the media, here in the area of the sample receiving plates 12, takes place. This is the sensitive area where a straight air cushion made of purified air should protect the media from contamination.
To achieve the above object of the invention is on the housing 1, preferably on the ceiling 4, the rear wall 5 or a side wall 6, a filter device 14 arranged for ambient air. In the illustrated preferred embodiment, the filter device 14 is located on the ceiling 4 and rear wall 5 of the housing first
The filter device 14 is fluidly connected via at least one air outlet 15 to the working space 8 of the housing 1. The filter device 14 has at least one air inlet 16 connected to the environment. Downstream of the air inlet 16 and upstream of the air outlet 15, the filter device 14 also has a fan 17 and at least one air filter 18.
By means of the filter device 14 is conveyed from the air outlet 15 from a filter air flow 19 into the working space 8 into it. As a result, as a result, the working space 8 in the housing 1 with respect to the environment under a certain, if only slight overpressure maintained, so that prevents contaminated air from the environment of the housing 1 in the working space 8 and in particular in the working area 13 in the working space 8 penetrates.
1 to 4 can now further be seen that according to the invention, at least one discharge opening 20 is structurally provided on the housing 1 in a coordinated with the position of the at least one air outlet 15 area. In the illustrated embodiment, one sees the at least one outflow opening 20 in Fig. 1 in the movable front wall 7 and in Fig. 3 on the closed front wall 7. The at least one air outlet 15 can be seen in the
Sectional views according to FIGS. 3 and 4, but in particular also in the isometric view of the filter device 14 in FIG. 6.
3, it can be seen that according to the invention the at least one air outlet 15 on the one hand and the at least one outflow opening 20 on the other hand are arranged on the housing 1 so that when operating the filter device 14 of the filter air stream 19 substantially parallel to and flows along the working area 13 in the working space 8, preferably substantially horizontally through or along the working area 13. In Fig. 3 and 4, this is indicated by a running from right to left arrow.
According to the invention it is essential that the filter air flow 19, which consists of particle-free and germ-free, perfectly filtered air, in the working area 13 laminar and substantially horizontally flows past and over the sample receiving plates 12 and the laboratory equipment 11 and the movement device 10. This prevents contamination of the media as far as possible.
The filter air flow 19 is as clean as the filters are selected in their retention capacity. Measurements have shown with HEPA filter H14 that in the working area 13 of the working space 8 the clean room class 5 can be reached.
Fig. 3 shows the exact construction according to this preferred embodiment of the invention such that the working area 13, with its arithmetic center plane, is arranged at a certain height above the bottom 2 of the housing 1. The at least one air outlet 15 and the at least one outflow opening 20 are arranged approximately in the plane of the working area 13 or slightly higher than the plane of the working area 13. In the illustrated and preferred exemplary embodiment, the position of the arrow representing the filter air flow 19 shows that the at least one air outlet 15 and the at least one outflow opening 20 are slightly higher in relation to the base 2 than the plane of the working area 13.
In the illustrated and preferred embodiment, the at least one air outlet 15 and the at least one outflow opening 20 are located approximately at the same height above the bottom 2 of the housing 1, namely the at least one air outlet 15 in the rear wall 5 and the at least one outflow opening 20 in the front wall 7.
Not shown is an arrangement of sample receiving plates at different heights to the bottom 2. Such a stepped arrangement defines an obliquely extending in the working space 8 working area 13. In order to achieve the object of the invention, the at least one air outlet 15 and the opposite at least one Outflow opening 20 offset in height to the bottom 2 and / or have to the bottom 2 an inclination.
In general, it can be provided that the at least one air outlet 15 are arranged on a side wall 6 and the at least one outflow opening 20 on the opposite side wall 6 of the housing 1. Here and preferably it is provided that the at least one air outlet 15 are arranged on the rear wall 5 and the at least one outflow opening 20 in the front wall 7.
With the illustrated and insofar preferred arrangement of the at least one air outlet 15 and the at least one outflow opening 20 is achieved as an additional advantage that even when opening the front wall 7, the direction of the filter air flow 19 remains unchanged. Even when the front wall 7 is open, there is a shielding of the working area 13 from the filter air flow 19, which still extends from the rear wall 5, in relation to the outside of incoming unfiltered air. This is cheaper than if the arrangements were made in the sidewalls.
The illustrated and preferred embodiment also shows that the inventive filter device 14 has an electronic control 21, with the aid of the air delivery of the fan 17 of the filter device 14 can be controlled or regulated. Further provided is a sensor assembly 22 which is connected to the controller 21 and with which the air pressure at the appropriate location in the housing 1 and outside the housing 1 can be measured.
According to the invention is provided according to a preferred teaching that the filter air flow 19 at the at least one air outlet 15 has a flow rate of 0.15 to 0.6 m / s, preferably from about 0.3 m / s. Furthermore, according to a preferred teaching of the invention, the operation of the filter device 14 is recommended in such a way that an air exchange rate of at least 20 / h, preferably from 50 / h to 200 / h, is achieved. According to a particularly preferred teaching of the invention, an air exchange rate of about 125 / h is provided in the concrete embodiment shown.
With the previously described settings, attempts are made to achieve a balance between the required volume of the filter air flow 19 on the one hand and the swirling above or below the filter air flow 19, if possible, to be avoided.
By means of the sensor arrangement 22, the air pressure in the working space 8 can be measured and the fan 17 is controlled by the controller 21 so that there is always a sufficient feed of filter air into the working space 8, in particular in the working area 13.
3 and 4 show in section, as already discussed, the position of the front wall 7 of the housing 1 with the front side closed (FIG. 3) and with the front side open (FIG. 4). In that regard, according to the invention is provided according to preferred teaching that the fan 17 of the filter device 14 is connected to the movable front wall 7 control technology and that, preferably, the fan 17 is controlled so that in the open position of the front wall 7, a larger filter air flow 19 can be generated than with Due to the realized in the illustrated and preferred embodiment alignment of the filter air flow 19 above and / or in the work area 13 of the rear wall 5 to the front wall 7, this results in a further improved operating situation for the laboratory device 9 in the housing 1.
For the filter device 14 can be made of various suggestions from the prior art. The illustrated in Fig. 3, 4 and 5 preferred embodiment is characterized insofar by the fact that the filter device 14 has an HEPA filter 18 as an air filter 18. Preferably, the filter device 14 upstream of the air filter 18, preferably at the at least one air inlet 16, a pre-filter 23. Downstream of the air filter 18, preferably at the at least one air outlet 15, there is preferably a secondary filter 24.
Preferably, the air filter 18 and / or the pre-filter 23 and / or the post-filter 24 are interchangeable. A pre-filter 23 provides for a longer service life of the air filter 18, which is particularly important when it is a relatively expensive HEPA filter 18. The post-filter 24 holds back contaminants on the at least one air outlet 15.
Then, if according to the preferred teaching of the after-filter 24 is arranged on the at least one air outlet 15 over the entire surface, as shown for example in Fig. 6, the post-filter 24 generates at the at least one air outlet 15 a defined flow resistance, so that the filter air flow 19 flows with largely uniform volume flow over the entire width or the entire opening cross sections of the at least one air outlet 15.
HEPA filters are classified as such in DIN EN 1822-1 and are already described as special clean room filters in DE 60 2004 010 578 T2. A concrete example of a HEPA filter 18 is of the H14 type.
Figures 3, 4, 5 and 6, in conjunction, disclose further particularly preferred aspects of the invention. Here, the filter device 14 has an antechamber 25 which is delimited by the prefilter 23 and the air filter 18 (here a HEPA filter). Further, here is a pressure chamber 26 which is bounded by the air filter 18 and the post-filter 24. One recognizes the housing 27 of the filter device 14 and, in FIGS. 1 and 2, the end-side air inlet 16.
According to a preferred teaching, it is provided that by means of the sensor assembly 22, the pressure in the pressure chamber 26 is measurable and by means of the controller 21, the fan 17 is controlled so that in the pressure chamber 26, a between 50 Pa and 150 Pa higher pressure than outside of the housing 1 is present.
Fig. 6 shows in the local embodiment, a single air outlet 15 of the filter device 14, which is designed as an elongated in the horizontal direction outlet opening with thereto Nachfilter 24. The post-filter 24 may consist of a filter mat with the action of a plurality of microscopic air outlets defined by the porosity of the post-filter 24. In addition to this filtering effect arises due to the porosity at the at least one air outlet 15, a defined flow resistance, which generates the increase in pressure in the pressure chamber 26 authoritative. By means of the pressure difference between the pressure chamber 26 and the interior of the housing 1 results in a gleichmäs-sig from the post-filter 24 over its entire width effluent filter air flow 19 into the working space 8 inside.
On the opposite front wall 7 of the housing 1 can be seen, as can be seen in FIGS. 1 and 2, a plurality of outflow openings 20 which are arranged in this area as in a kind of perforated plate. The arrangement and size of the outflow openings 20 is also influenced by the fact that in any case any unwanted intrusion into the working space 8 in the housing 1 must be reliably avoided.
According to the preferred teaching and as shown in Fig. 3 it is provided that the position of the outflow openings 20 in the front wall 7 approximately corresponds to the position of the air filter 15 provided with the postfilter 24 in the rear wall 5.
By means of the sensor arrangement 22 and the controller 21, the filter occupancy, so the pollution of the filter can be checked and signaled to a user. The filter air flow 19 can be monitored. The delivery volume of the fan 17 can be adapted to the filter assignment. Overall, with this arrangement, a full-fledged regulation for the fan 17 of the filter device 14 can be achieved.
According to the invention, a slight overpressure is to be maintained in the working space 8, in particular at the working area 13, in the housing 1, as has already been explained in the prior art. This avoids that air can penetrate from the outside into the housing 1 unintentionally. A small proportion of the filter air flow 19 flowing into the working space 8 of the housing 1 can escape via unintentionally but unavoidably existing gaps. The largest part of the filter air flow 19 should escape via the outflow openings 20. According to a preferred teaching of the invention, it is provided that the sum of the free cross sections of all outflow openings 20 is between 20% and 80%, preferably between 25% and 50%, of the sum of the free cross sections of all air outlets 15.
Figs. 1 and 2 show that the plurality of outflow openings 20 provided in the illustrated and preferred embodiment together form a wide drawn, horizontally disposed region of outflow openings 20, which is the wide, two-dimensional air outlet 15 with the Postfilter 24, in arrangement and orientation substantially corresponds.
The illustrated and so far preferred embodiment can be seen in Fig. 3 and 4 well that the working space 8 in the housing 1 has a certain inner clear height and that the at least one air outlet 15 and / or the at least one outflow opening 20, from the Measured from top of the bottom 2, extending in a range between 15% and 45%, preferably in a range between 20% and 35%, the clear height of the working space 8.
权利要求:
Claims (13)
[1]
According to FIG. 1 and FIG. 6, the at least one air outlet 15 is located on the rear wall 5 and the at least one outflow opening 20 is on the front wall 7. In that regard, it is particularly expedient according to the particularly preferred and illustrated teaching of the invention the at least one air outlet 15 and / or the at least one outflow opening 20 extends in the direction of the width of the rear wall 5 or the front wall 7. It is particularly preferred if the air outlet region formed by the at least one air outlet 15 extends symmetrically over 70% to 90%, preferably approximately 80%, of the clear width of the rear wall 5 in the working space 8 on the rear wall 5. In the same way, the region of the outflow openings 20 is designed on the front wall 7. With the particular arrangement of the air outlets 15 and the outflow openings 20, one can influence and adjust the orientation of the filter air flow 19. For example, the density of the openings towards the side walls 6 can be increased in order to counteract the diffused outlet of the filter air flow on columns of the side walls. A further influencing of the filter air flow 19 is made possible by the fact that adjustable guide vanes are arranged downstream of the at least one air outlet 15 for guiding the filter air flow 19. FIG. 5 shows the housing 1 according to the invention in a plan view. Shown in dashed lines are the components of the filter device 14 arranged in the housing 27 of the filter device 14. It can be seen in FIG. 6 that in the preferred exemplary embodiment illustrated and preferred, the filter device 14 is an independent module. This assembly in total can be grown instead of the rear wall 5 to an existing housing 1. The upper part of the filter device 14 with the housing 27 is located above the ceiling 4 of the housing 1, the rest of the filter device 14 replaces on the housing 1 a previously removed rear wall 5. An alternative is to design the filter device 14 as an integral one from the outset To construct part of the housing 1. Fig. 7 shows the path of Fi Iteri uftstroms 19 from the outside into the working space 8 and in particular there the working area 13 in the housing 1 and back out into the environment. claims
1. Housing for a laboratory device, with bottom (2), ceiling (4), rear wall (5), side walls (6) and front wall (7), which together form a work space enclosed by them (8), wherein the front wall (7 ) relative to the housing (1) is movable between a closed position and an open position, wherein in the closed position of the front wall (7) of the working space (8) is not accessible from the outside and wherein in the open position of the front wall (7) of the working space (8) on the front side of the housing (1) is accessible from the outside, wherein, preferably, in the working space (8) a movement device (10) for laboratory equipment (11) is arranged, wherein in the working space (8) aligned in a plane working area (13 ) is provided, in which liquids can be handled, wherein on the housing (1), on the rear wall (5) or on a side wall (6) and optionally on the ceiling (4) a filter device (14) is arranged for ambient air, the flow over at least one air outlet (15) is connected to the working space (8) of the housing (1), the filter device (14) comprising at least one ambient air inlet (16) and downstream of the at least one air inlet (16) and upstream of the at least one Air outlet (15) has a fan (17) and at least one air filter (18), and wherein by means of the filter device (14) from the at least one air outlet (15) from a filter air flow (19) into the working space (8) is conveyed into, characterized in that on the housing (1) in a matched to the position of the at least one air outlet (15) at least one outlet opening (20) is deliberately structurally provided and that the at least one air outlet (15) on the one hand and the at least one outflow opening (20 On the other hand, on the housing (1) are arranged so that during operation of the filter device (14) of the filter air flow (19) substantially parallel to and along the Work area (13) flows.
[2]
2. Housing according to claim 1, characterized in that the working area (13) at a certain height above the bottom (2) of the housing (1) is arranged and / or that the filter air flow (19) substantially horizontally in the working space (8 ) flows through and / or along the working area (13).
[3]
3. Housing according to claim 1 or 2, characterized in that the at least one air outlet (15) and the at least one outflow opening (20) in the plane of the working area (13) or, preferably, with respect to the bottom (2) higher than that Plane of the work area (13) are arranged.
[4]
4. Housing according to one of the preceding claims, characterized in that the at least one air outlet (15) on a side wall (6) and the at least one outflow opening (20) on the opposite side wall (6) of the housing (1) are arranged or in that the at least one air outlet (15) is arranged on the rear wall (5) and the at least one outflow opening (20) is arranged in the front wall (7).
[5]
5. Housing according to one of the preceding claims, characterized in that the filter device (14) is provided with a controller (21) at least for the fan (17) that the fan (17) of the filter device (14) is controllable such that the filter air flow (19) at the air outlet (15) has a speed of 0.15 to 0.60 m / sec, wherein, preferably, an air exchange rate of at least 20 / h, preferably from 50 / h to 200 / h is achievable and / or that the air pressure in the housing (1) and outside the housing (1) can be measured and by means of the controller (21) the fan (17) is controllable such that in the working space (8) a slight overpressure with respect to the pressure outside of the Housing (1) can be generated.
[6]
6. Housing according to one of the preceding claims, characterized in that the fan (17) of the filter device (14) with the movable front wall (7) is connected control technology and that, preferably, the fan (17) is controlled so that in the Opening position of the front wall (7) a larger filter air flow (19) can be generated than in the closed position of the front wall (7).
[7]
7. Housing according to one of the preceding claims, characterized in that the filter device (14) as an air filter (18) has a HEPA filter (18).
[8]
8. Housing according to one of the preceding claims, characterized in that the filter device (14) upstream of an air filter (18), in particular the HEPA filter (18), preferably at the at least one air inlet (16), a pre-filter (23). having.
[9]
9. Housing according to one of the preceding claims, characterized in that the filter device (14) on the at least one air outlet (15) has a post-filter (24) which is arranged there over the entire surface and by the at least one air outlet (15) defined flow resistance is generated.
[10]
10. Housing according to claim 9, characterized in that the filter device (14) has a pressure chamber (26) which is delimited by the air filter (18) and the post-filter (24), and that, preferably, by means of a sensor arrangement (22). the pressure in the pressure chamber (26) is measurable and by means of the controller (21) the fan (17) is controllable such that a pressure between 50 Pa and 150 Pa is present in the pressure chamber (26) than outside the housing (1) ,
[11]
11. Housing according to one of the preceding claims, characterized in that the sum of the free cross sections of all outflow openings (20) between 20% and 80%, preferably between 25% and 50%, the sum of the free cross sections of all air outlets (15).
[12]
12. Housing according to one of the preceding claims, characterized in that a plurality of air outlets (15) is provided, which are preferably not arranged uniformly distributed, and / or that a plurality of outflow openings (20) is provided which preferably not evenly distributed are arranged.
[13]
13. Housing according to one of the preceding claims, characterized in that downstream of the at least one air outlet (15) adjustable guide vanes for guiding the filter air flow (19) are arranged.
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同族专利:
公开号 | 公开日
CH712504B1|2021-05-14|
CH712504B8|2021-07-15|
DE202017002012U1|2017-08-21|
US10926266B2|2021-02-23|
US20170333907A1|2017-11-23|
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法律状态:
2021-06-15| PK| Correction|Free format text: BERICHTIGUNG ERFINDER |
优先权:
申请号 | 申请日 | 专利标题
DE202016003110|2016-05-17|
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